![]() ![]() So far, different developments regarding growth rates and case numbers have been observed for each respective country as they pass through the initial stages of the outbreak. Although there are different approaches to attain COVID-19 containment, the goal of reducing interactions between unidentified infected with noninfected individuals remains unchanged. Significant global COVID-19 epicenters include Italy, France, Spain, Iran, South Korea, Japan, Germany and the initial place of the outbreak, China. International flight traffic has been majorly affected and many countries report increased COVID-19 numbers. 1 Current knowledge of the biology and transmission of this virus remains limited 2, 3 and COVID-19's final mortality rates are subject to rough estimation. ![]() Thus, with continuously rising numbers of confirmed cases, COVID-19 has been declared a pandemic on March 11th, 2020 by Tedros Ghebreyesus, the World Health Organization's (WHO) Director-General. The current COVID-19 outbreak with multiple global epicenters has attracted worldwide attention. Based on our data, disease management in the 2 weeks following the first reported cases is of utmost importance. Although the initial data in Asian countries are encouraging with respect to case development at the initial stage, the opposite is true for European countries. Interestingly, the rates for Germany, Spain, and France are the highest measured in the second interval and even surpass the numbers in Italy. For European countries, the growth rate of COVID-19 cases considerably increased during the second time interval. Although the growth rate of total confirmed COVID-19 cases in China has decreased, those for Japan have remained constant. Growth rates and doubling time of cases were calculated for the first 6 weeks after the initial cases were declared for each respective country and put into context with implemented policies. We analyzed available data on COVID-19 cases of eight majorly affected countries, including China, Italy, Iran, Germany, France, Spain, South Korea, and Japan. However, the efficacy of individual policies remains unclear with respect to COVID-19 case development. Consequently, many countries have implemented different policies to manage this crisis including curfew and lockdown. With multiple virus epicenters, COVID-19 has been declared a pandemic by the World Health Organization.
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